Curvature of the penis is an abnormal bend in the penis that occurs during erection. It is also called Peyronie’s disease.
In Peyronie’s disease, fibrous scar tissue develops under the skin of the penis. The cause of this fibrous tissue is not known. Fracture of the penis can lead to this condition. Patients have a higher risk after surgery or radiation treatment for prostate cancer. Peyronie’s disease is uncommon and affects men ages 40 – 60 and older. Curvature of the penis can occur with Dupuytren’s contracture, a cord-like thickening across the palm of one or both hands. It is a fairly common disorder in white men over age 50. However, only a very small number of people with Dupuytren’s contracture develop curvature of the penis.
Other risk factors have not been found. However, people with this condition have a certain type of immune cell marker, which indicates that it may be inherited. Newborns may have a curvature of the penis, which may be part of an abnormality called hypospadias (this is different from Peyronie’s disease).
You or your doctor may notice an abnormal hardening of the tissue below the skin, in one area along the shaft of the penis. During erection, there may be:
Vitamin E is found naturally in some food but it is also available as dietary supplement. It is maybe best known for its antioxidant properties, it helps protecting cells from potential damage caused by free radicals, like pollution, in the environment. Vitamin E may also help with scar prevention and that is why it has been recommended for Peyronie’s patients. Vitamin E may be able to hinder scar tissue building up and to reduce inflammation.
Some newer agents targeting the basic mechanisms of inflammation have been studied in larger clinical trials. These include potassium para-aminobenzoate (Potaba), pentoxifylline (acting through TGFβ1 inhibition) and Coenzyme Q10. Other newer agents of interest include acetyl L-carnitine, propionyl L-carnitine, L-arginine, and sildenafil (acting through phosphodiesterase-5 inhibition). The efficacy of Interferon-alpha-2b in the early stages of the disease has been reported in recent publications but it was found to be less effective in cases where calcification of the plaque had occurred in common with many treatments.
The two most common surgeries used to treat Peyronie’s disease are:
Unfortunately, the surgeries do not guarantee normal penis function. The first method can involve partial loss of erectile function, especially rigidity. The second method, known as the Nesbit procedure, causes a shortening of the erect penis. Another surgery for Peyronie’s disease is penile prosthesis implantation. This treatment is reserved for men who have both Peyronie’s disease and significant erectile dysfunction (inability to obtain or maintain an erection suitable for intercourse). Most types of surgery produce positive results. But because complications can occur, and because many of the complications associated with Peyronie’s disease (for example, shortening of the penis) cannot be corrected, most doctors prefer to perform surgery only on the small number of men with curvature so severe that it prevents sexual intercourse.
Dr Mahendra Jain is an eminent and an extremely experienced Urologist ...Read More
I had undergone treatment for my prostate in Germany 5 years back. Now I developed urethral stricture, I had lot of problem passing urine.
Mr Alexis is aged 72 yrs from East Africa was treated for his long standing urinary problem with a complex surgery. Now he is back in his country